Antibody repertoire analysis in polygenic autoimmune diseases

High-throughput sequencing of the DNA/RNA encoding antibody heavy- and light-chains is rapidly transforming the field of adaptive immunity. It can address key questions, including: (i) how the B-cell repertoire differs in health and disease; and (ii) if it does differ, the point(s) in B-cell develop...

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Hlavní autoři: Bashford-Rogers, R, Smith, K, Thomas, D
Médium: Journal article
Jazyk:English
Vydáno: Wiley 2018

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