Antibody repertoire analysis in polygenic autoimmune diseases
High-throughput sequencing of the DNA/RNA encoding antibody heavy- and light-chains is rapidly transforming the field of adaptive immunity. It can address key questions, including: (i) how the B-cell repertoire differs in health and disease; and (ii) if it does differ, the point(s) in B-cell develop...
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
Wiley
2018
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