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Large scale case-control and family-based analyses of TCF7L2 variants in > 6000 UK subjects demonstrates an almost two-fold difference in relative risk between homozygote classes

Large scale case-control and family-based analyses of TCF7L2 variants in > 6000 UK subjects demonstrates an almost two-fold difference in relative risk between homozygote classes

Dades bibliogràfiques
Autors principals: Groves, C, Zeggini, E, Minton, J, Frayling, T, Weedon, M, Rayner, N, Hitman, G, Walker, M, Wiltshire, S, Hattersley, A, McCarthy, M
Format: Conference item
Publicat: 2006
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  • Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk.
    per: Groves, C, et al.
    Publicat: (2006)
  • Combining information from common type 2 diabetes risk polymorphisms improves disease prediction
    per: Weedon, M, et al.
    Publicat: (2006)
  • Combining information from common type 2 diabetes risk polymorphisms improves disease prediction.
    per: Weedon, M, et al.
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  • Type 2 diabetes transcription factor 7-like 2 (TCF7L2) risk alleles reduce beta-cell function and increase birth weight
    per: Freathy, R, et al.
    Publicat: (2007)
  • Large-scale association studies of candidate genes and their interactions in Type 2 diabetes
    per: Zeggini, E, et al.
    Publicat: (2004)

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