Large scale case-control and family-based analyses of TCF7L2 variants in > 6000 UK subjects demonstrates an almost two-fold difference in relative risk between homozygote classes

Míreanna comhchosúla

• Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk.
  de réir: Groves, C, et al.
  Foilsithe / Cruthaithe: (2006)
• Combining information from common type 2 diabetes risk polymorphisms improves disease prediction
  de réir: Weedon, M, et al.
  Foilsithe / Cruthaithe: (2006)
• Combining information from common type 2 diabetes risk polymorphisms improves disease prediction.
  de réir: Weedon, M, et al.
  Foilsithe / Cruthaithe: (2006)
• Type 2 diabetes transcription factor 7-like 2 (TCF7L2) risk alleles reduce beta-cell function and increase birth weight
  de réir: Freathy, R, et al.
  Foilsithe / Cruthaithe: (2007)
• Large-scale association studies of candidate genes and their interactions in Type 2 diabetes
  de réir: Zeggini, E, et al.
  Foilsithe / Cruthaithe: (2004)