Phenytoin pharmacokinetics and clinical effects in African children following fosphenytoin and chloramphenicol coadministration.
AIMS: Some children with malaria and convulsions also have concurrent bacterial meningitis. Chloramphenicol is used to treat the latter whereas phenytoin is used for convulsions. Since chloramphenicol inhibits the metabolism of phenytoin in vivo, we studied the effects of chloramphenicol on phenyto...
Main Authors: | Ogutu, B, Newton, C, Muchohi, SN, Otieno, G, Kokwaro, G |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2002
|
Similar Items
-
Pharmacokinetics and clinical effects of phenytoin and fosphenytoin in children with severe malaria and status epilepticus.
by: Ogutu, B, et al.
Published: (2003) -
Chloramphenicol pharmacokinetics in African children with severe malaria.
by: Kokwaro, G, et al.
Published: (2006) -
Pharmacokinetics and clinical effect of phenobarbital in children with severe falciparum malaria and convulsions.
by: Kokwaro, G, et al.
Published: (2003) -
Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers
by: Xiaojiao Li, et al.
Published: (2023-11-01) -
Pharmacokinetics and clinical efficacy of lorazepam in children with severe malaria and convulsions.
by: Muchohi, SN, et al.
Published: (2008)