Phenytoin pharmacokinetics and clinical effects in African children following fosphenytoin and chloramphenicol coadministration.

Phenytoin pharmacokinetics and clinical effects in African children following fosphenytoin and chloramphenicol coadministration.

AIMS: Some children with malaria and convulsions also have concurrent bacterial meningitis. Chloramphenicol is used to treat the latter whereas phenytoin is used for convulsions. Since chloramphenicol inhibits the metabolism of phenytoin in vivo, we studied the effects of chloramphenicol on phenyto...

Полное описание

Библиографические подробности
Главные авторы:	Ogutu, B, Newton, C, Muchohi, SN, Otieno, G, Kokwaro, G
Формат:	Journal article
Язык:	English
Опубликовано:	2002

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