RANKL-independent human osteoclast formation with APRIL, BAFF, NGF, IGF I and IGF II.

Non-canonical pathways of osteoclastogenesis have been described in which several cytokines are able to substitute for RANKL. These cytokines are few in number and their role(s) in pathological bone resorption has not been ascertained. We have identified five additional cytokines, APRIL, BAFF, NGF,...

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Hlavní autoři: Hemingway, F, Taylor, R, Knowles, H, Athanasou, N
Médium: Journal article
Jazyk:English
Vydáno: 2011