Oligomerization-driven avidity correlates with SARS-CoV-2 cellular binding and inhibition

Cellular processes are controlled by the thermodynamics of the underlying biomolecular interactions. Frequently, structural investigations use one monomeric binding partner, while ensemble measurements of binding affinities generally yield one affinity representative of a 1:1 interaction, despite th...

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Detaylı Bibliyografya
Asıl Yazarlar: Asor, R, Olerinyova, A, Burnap, SA, Kushwah, M, Soltermann, F, Rudden, LSP, Hensen, M, Vasiljevic, S, Brun, J, Hill, M, Chang, L, Dejnirattisa, W, Supasa, P, Mogkolsapaya, J, Zhou, D, Stuart, D, Screaton, GR, Degiacomi, M, Zitzmann, N, Benesch, J, Struwe, W, Kukura, P
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: National Academy of Sciences 2024