Oligomerization-driven avidity correlates with SARS-CoV-2 cellular binding and inhibition
Cellular processes are controlled by the thermodynamics of the underlying biomolecular interactions. Frequently, structural investigations use one monomeric binding partner, while ensemble measurements of binding affinities generally yield one affinity representative of a 1:1 interaction, despite th...
| Главные авторы: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Формат: | Journal article |
| Язык: | English |
| Опубликовано: |
National Academy of Sciences
2024
|