Delayed boosting improves human antigen-specific Ig and B cell responses to the RH5.1/AS01B malaria vaccine

Delayed boosting improves human antigen-specific Ig and B cell responses to the RH5.1/AS01B malaria vaccine

<p>Modifications to vaccine delivery that increase serum antibody longevity are of great interest for maximizing efficacy. We have previously shown that a delayed fractional (DFx) dosing schedule (0-1-6 month) &mdash; using AS01<sub>B</sub>-adjuvanted RH5.1 malaria antigen &...

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প্রধান লেখক: Nielsen, CM, Barrett, JR, Davis, C, Fallon, JK, Goh, C, Michell, AR, Griffin, C, Kwok, A, Loos, C, Darko, S, Laboune, F, Tekman, M, Diouf, A, Miura, K, Francica, JR, Ransier, A, Long, CA, Silk, SE, Payne, RO, Minassian, AM, Lauffenburger, DA, Seder, RA, Douek, DC, Alter, G, Draper, SJ
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: American Society for Clinical Investigation 2023

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