Functional dissection of a single enhancer at the mouse α-globin locus

<p>Enhancers are cis-regulatory DNA elements that bind transcription factors and drive expression of target genes in a spatio-temporal manner. Despite their collective importance in cell fate specification, up to now enhancers have often been studied in assays that ignore the chromosomal conte...

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Bibliographic Details
Main Author: Francis, H
Other Authors: Kassouf, M
Format: Thesis
Language:English
Published: 2019