Functional dissection of a single enhancer at the mouse α-globin locus
<p>Enhancers are cis-regulatory DNA elements that bind transcription factors and drive expression of target genes in a spatio-temporal manner. Despite their collective importance in cell fate specification, up to now enhancers have often been studied in assays that ignore the chromosomal conte...
Main Author: | Francis, H |
---|---|
Other Authors: | Kassouf, M |
Format: | Thesis |
Language: | English |
Published: |
2019
|
Similar Items
-
Genetic dissection of the α-globin super-enhancer in vivo
by: Hay, D, et al.
Published: (2016) -
The mouse alpha-globin locus regulatory element.
by: Gourdon, G, et al.
Published: (1995) -
Understanding fundamental principles of enhancer biology at a model locus: analysing the structure and function of an enhancer cluster at the α-globin locus
by: Kassouf, M, et al.
Published: (2023) -
Analysis of a gain-of-function mutation that produces a new transcriptional unit in the α-globin locus
by: Bozhilov, Y
Published: (2017) -
High-resolution analysis of cis-acting regulatory networks at the α-globin locus.
by: Hughes, J, et al.
Published: (2013)