Mechanistic insights into arrhythmogenic right ventricular cardiomyopathy caused by desmocollin-2 mutations.

AIMS: Recent immunohistochemical studies observed the loss of plakoglobin (PG) from the intercalated disc (ID) as a hallmark of arrhythmogenic right ventricular cardiomyopathy (ARVC), suggesting a final common pathway for this disease. However, the underlying molecular processes are poorly understoo...

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Bibliographic Details
Main Authors: Gehmlich, K, Syrris, P, Peskett, E, Evans, A, Ehler, E, Asimaki, A, Anastasakis, A, Tsatsopoulou, A, Vouliotis, A, Stefanadis, C, Saffitz, J, Protonotarios, N, McKenna, W
Format: Journal article
Language:English
Published: 2011