Identification of inhibitors for a family of human oxoglutarate-dependent oxygenases

<p>The family of human iron- and 2-oxoglutarate - dependent oxygenases encompasses over 60 members and a subclass of the enzymes, containing Jumonji C (JmjC) domain, is directly involved in epigenetic control of gene transcription, through demethylation of methyl marks present on histone tails...

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Bibliographic Details
Main Author: Nowak, R
Other Authors: Oppermann, U
Format: Thesis
Language:English
Published: 2015
Subjects: