Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactions.

Small molecules which can mimic the key structural facets of protein secondary structure, in particular the α-helix, β-strand, and β-sheet, have been shown to be potent disruptors of protein-protein interactions. Researchers have recently taken the organizational imitation of protein secondary struc...

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Bibliographic Details
Main Authors: Adler, M, Jamieson, A, Hamilton, A
Format: Journal article
Language:English
Published: 2011