Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactions.
Small molecules which can mimic the key structural facets of protein secondary structure, in particular the α-helix, β-strand, and β-sheet, have been shown to be potent disruptors of protein-protein interactions. Researchers have recently taken the organizational imitation of protein secondary struc...
Main Authors: | Adler, M, Jamieson, A, Hamilton, A |
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Format: | Journal article |
Language: | English |
Published: |
2011
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