Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactions.

Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactions.

Small molecules which can mimic the key structural facets of protein secondary structure, in particular the α-helix, β-strand, and β-sheet, have been shown to be potent disruptors of protein-protein interactions. Researchers have recently taken the organizational imitation of protein secondary struc...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Adler, M, Jamieson, A, Hamilton, A
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	2011

Míreanna comhchosúla

Synthetic Peptides as Protein Mimics
de réir: Andrea eGroß, et al.
Foilsithe / Cruthaithe: (2016-01-01)

Synthetic mimetics of protein secondary structure domains.
de réir: Ross, N, et al.
Foilsithe / Cruthaithe: (2010)

Protein-Protein Interaction Disruptors of the YAP/TAZ-TEAD Transcriptional Complex
de réir: Ajaybabu V. Pobbati, et al.
Foilsithe / Cruthaithe: (2020-12-01)

Disruptor: Computational identification of oncogenic mutants disrupting protein-protein and protein-DNA interactions
de réir: Valentina Kugler, et al.
Foilsithe / Cruthaithe: (2023-07-01)

Effect of hydrogen bond interaction on protein phase transition
de réir: Leong, Hon Wai, et al.
Foilsithe / Cruthaithe: (2013)

Dynamics of hydrogen bonds in the secondary structures of allosteric protein Avena Sativa phototropin 1
de réir: Mayar Tarek Ibrahim, et al.
Foilsithe / Cruthaithe: (2022-01-01)

Funneling modulatory peptide design with generative models: Discovery and characterization of disruptors of calcineurin protein-protein interactions.
de réir: Jérôme Tubiana, et al.
Foilsithe / Cruthaithe: (2023-02-01)

Ice-binding proteins and bioinspired synthetic mimics in non-physiological environments
de réir: Elizabeth A. Delesky, et al.
Foilsithe / Cruthaithe: (2022-05-01)

Structure and Function of Canine SP-C Mimic Proteins in Synthetic Surfactant Lipid Dispersions
de réir: Frans J. Walther, et al.
Foilsithe / Cruthaithe: (2024-01-01)

A study on protein secondary structure phase transition based on an effective hydrogen bonding potential
de réir: Leong, Hon Wai
Foilsithe / Cruthaithe: (2013)

Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation.
de réir: Anthony W Fitzpatrick, et al.
Foilsithe / Cruthaithe: (2011-10-01)

Mimics of copper proteins: structural and functional aspects
de réir: ANA MARIA DA COSTA FERREIRA, et al.
Foilsithe / Cruthaithe: (2000-03-01)

Analysis of Protein-Protein Interactions for Intermolecular Bond Prediction
de réir: Justin Z. Tam, et al.
Foilsithe / Cruthaithe: (2022-09-01)

Leveraging Hot Spots of TEAD–Coregulator Interactions in the Design of Direct Small Molecule Protein-Protein Interaction Disruptors Targeting Hippo Pathway Signaling
de réir: Bin Zhao, et al.
Foilsithe / Cruthaithe: (2023-04-01)

SuperMimic – Fitting peptide mimetics into protein structures
de réir: Schmidt Ulrike, et al.
Foilsithe / Cruthaithe: (2006-01-01)

Synthetic Endocrine Disruptors in Fragranced Products
de réir: Sawyer Ashcroft, et al.
Foilsithe / Cruthaithe: (2024-08-01)

Evolution of strategies to prepare synthetic mimics of carboxylate-bridged diiron protein active sites
de réir: Do, Loi Hung, et al.
Foilsithe / Cruthaithe: (2017)

Synthetic Protein Circuits and Devices Based on Reversible Protein-Protein Interactions: An Overview
de réir: Stefano Rosa, et al.
Foilsithe / Cruthaithe: (2021-11-01)

Protein nanofibril design via manipulation of hydrogen bonds
de réir: Nidhi Aggarwal, et al.
Foilsithe / Cruthaithe: (2021-05-01)

A tensegrity model for hydrogen bond networks in proteins
de réir: Robert P. Bywater
Foilsithe / Cruthaithe: (2017-05-01)

Hydrogen Bond Dynamic Propensity Studies for Protein Binding and Drug Design.
de réir: Cintia A Menéndez, et al.
Foilsithe / Cruthaithe: (2016-01-01)

alpha-Helix mimetics as inhibitors of protein-protein interactions.
de réir: Saraogi, I, et al.
Foilsithe / Cruthaithe: (2008)

Structures, dynamics, and hydrogen-bond interactions of antifreeze proteins in TIP4P/Ice water and their dependence on force fields.
de réir: Hwankyu Lee
Foilsithe / Cruthaithe: (2018-01-01)

Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice
de réir: Paulino Barragán-Iglesias, et al.
Foilsithe / Cruthaithe: (2018-01-01)

Short Hydrogen Bonds and Proton Delocalization in Green Fluorescent Protein (GFP)
de réir: Luke M. Oltrogge, et al.
Foilsithe / Cruthaithe: (2015-06-01)

Mining protein networks for synthetic genetic interactions
de réir: Zhao Shan, et al.
Foilsithe / Cruthaithe: (2008-10-01)

Protein phosphatase 2A anchoring disruptor gene therapy for familial dilated cardiomyopathy
de réir: Xueyi Li, et al.
Foilsithe / Cruthaithe: (2024-06-01)

Noncovalent Hydrogen Bonds Tune the Mechanical Properties of Phosphoester Polyethylene Mimics
de réir: Hisaschi T. Tee, et al.
Foilsithe / Cruthaithe: (2019-05-01)

Hydrogen-bond networks for proton couplings in G-Protein coupled receptors
de réir: Ana-Nicoleta Bondar, et al.
Foilsithe / Cruthaithe: (2022-09-01)

Digital Operation of Microelectronic Circuits Analogous to Protein Hydrogen Bonding Networks
de réir: Elitsa Gieva, et al.
Foilsithe / Cruthaithe: (2012-12-01)

Role of Hydrogen Bonding in Green Fluorescent Protein-like Chromophore Emission
de réir: Li Yang, et al.
Foilsithe / Cruthaithe: (2019-08-01)

General synthetic strategy for regioselective ultrafast formation of disulfide bonds in peptides and proteins
de réir: Shay Laps, et al.
Foilsithe / Cruthaithe: (2021-02-01)

Diversity-oriented synthetic strategy for developing a chemical modulator of protein–protein interaction
de réir: Jonghoon Kim, et al.
Foilsithe / Cruthaithe: (2016-10-01)

Principles for the design and construction of synthetic circuits utilizing protein-protein interactions in Saccharomyces cerevisiae
de réir: Mishra, Deepak, Sc. D. Massachusetts Institute of Technology
Foilsithe / Cruthaithe: (2016)

Assembling and decorating hyaluronan hydrogels with twin protein superglues to mimic cell-cell interactions
de réir: Wieduwild, R, et al.
Foilsithe / Cruthaithe: (2018)

Plagiarizing proteins: enhancing efficiency in asymmetric hydrogen-bonding catalysis through positive cooperativity.
de réir: Jones, C, et al.
Foilsithe / Cruthaithe: (2009)

Oligomeric protein structure networks: insights into protein-protein interactions
de réir: Brinda KV, et al.
Foilsithe / Cruthaithe: (2005-12-01)

Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7
de réir: Fuzhou Ye, et al.
Foilsithe / Cruthaithe: (2020-02-01)

The Temperature Dependence of Hydrogen Bonds Is More Uniform in Stable Proteins: An Analysis of NMR h3JNC′ Couplings in Four Different Protein Structures
de réir: Alexandrescu, Andrei T., et al.
Foilsithe / Cruthaithe: (2024)

Exploration of small-molecule entry disruptors for chikungunya virus by targeting matrix remodelling associated protein
de réir: Avinash Kumar, et al.
Foilsithe / Cruthaithe: (2020-01-01)