Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects.
A promising strategy for cancer immunotherapy is to disrupt key pathways regulating immune tolerance, such as cytotoxic T lymphocyte-associated protein 4 (CTLA-4). However, the determinants of response to anti-CTLA-4 mAb treatment remain incompletely understood. In murine models, anti-CTLA-4 mAbs al...
| Главные авторы: | , , , , , , , , , |
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| Формат: | Journal article |
| Язык: | English |
| Опубликовано: |
2012
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