The role of extra-thymic AIRE-expressing cells (eTACs) in AIRE-propagated immune tolerance

<p>The autoimmune regulator (AIRE) is a facilitator of gene transcription found primarily in the thymus where its expression is localized primarily to mature medullary thymic epithelial cells (mTECs). AIRE modulates the promiscuous gene expression of tissue-restricted antigens (TRAs) and thus...

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Bibliographic Details
Main Author: Rosen, L
Other Authors: Holländer, G
Format: Thesis
Language:English
Published: 2021
Subjects: