Comparison of heterosubtypic protection in ferrets and pigs induced by a single-cycle influenza vaccine

Influenza is a major health threat, and a broadly protective influenza vaccine would be a significant advance. Signal Minus FLU (S-FLU) is a candidate broadly protective influenza vaccine that is limited to a single cycle of replication, which induces a strong cross-reactive T cell response but a mi...

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Bibliographic Details
Main Authors: Holzer, B, Morgan, S, Matsuoka, Y, Edmans, M, Salguero, F, Everett, H, Brookes, S, Porter, E, Macloughlin, R, Charleston, B, Subbarao, K, Townsend, A, Tchilian, E
Format: Journal article
Language:English
Published: American Association of Immunologists 2018