The anti-malarial drug atovaquone potentiates platinum-mediated cancer cell death by increasing oxidative stress

Platinum chemotherapies are highly effective cytotoxic agents but often induce resistance when used as monotherapies. Combinatorial strategies limit this risk and provide effective treatment options for many cancers. Here, we repurpose atovaquone (ATQ), a well-tolerated & FDA-approved anti-malar...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Coates, JTT, Rodriguez-Berriguete, G, Puliyadi, R, Ashton, T, Prevo, R, Wing, A, Granata, G, Pirovano, G, McKenna, GW, Higgins, GS
स्वरूप: Journal article
भाषा:English
प्रकाशित: Springer Nature 2020
विषय: