Extracellular ATP increases cytoplasmic free Ca2+ concentration in clonal insulin-producing RINm5F cells. A mechanism involving direct interaction with both release and refilling of the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool.
Effects of extracellularly applied ATP (added as disodium salt) on stimulus-secretion coupling were investigated in clonal insulin-producing RINm5F cells. Cytoplasmic free Ca2+ concentration [( Ca2+]i), electrical activity, membrane potential, formation of InsP3 and insulin release were measured. Ad...
Автори: | Arkhammar, P, Hallberg, A, Kindmark, H, Nilsson, T, Rorsman, P, Berggren, P |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
1990
|
Схожі ресурси
Схожі ресурси
-
Interaction with the inositol 1,4,5-trisphosphate receptor promotes Ca2+ sequestration in permeabilised insulin-secreting cells.
за авторством: Islam, MS, та інші
Опубліковано: (1991) -
Voltage-activated Na+ currents and their suppression by phorbol ester in clonal insulin-producing RINm5F cells.
за авторством: Rorsman, P, та інші
Опубліковано: (1986) -
Inositol trisphosphate-dependent periodic activation of a Ca(2+)-activated K+ conductance in glucose-stimulated pancreatic beta-cells.
за авторством: Ammälä, C, та інші
Опубліковано: (1991) -
Inositol 1,4,5-trisphosphate receptors in the heart.
за авторством: Mackenzie, L, та інші
Опубліковано: (2004) -
Inositol 1,4,5-trisphosphate receptors in the heart
за авторством: LAUREN MACKENZIE, та інші
Опубліковано: (2004-01-01)