Binding site flexibility: molecular simulation of partial and full agonists within a glutamate receptor.

Ionotropic glutamate receptors mediate fast synaptic transmission in the mammalian central nervous system and play an important role in many different functions, including memory and learning. They have also been implicated in a variety of neuropathologies and as such have generated widespread inter...

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Bibliographic Details
Main Authors: Arinaminpathy, Y, Sansom, MS, Biggin, P
Format: Journal article
Language:English
Published: 2006