Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis

High-risk endometrial cancer has poor prognosis and is increasing in incidence. However, understanding of the molecular mechanisms which drive this disease is limited. We used genetically engineered mouse models (GEMM) to determine the functional consequences of missense and loss of function mutatio...

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Bibliografske podrobnosti
Main Authors: Brown, M, Leon, A, Kedzierska, K, Moore, C, Belnoue-Davis, HL, Church, DN
Format: Journal article
Jezik:English
Izdano: EMBO Press 2023