Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis

High-risk endometrial cancer has poor prognosis and is increasing in incidence. However, understanding of the molecular mechanisms which drive this disease is limited. We used genetically engineered mouse models (GEMM) to determine the functional consequences of missense and loss of function mutatio...

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Bibliographic Details
Main Authors: Brown, M, Leon, A, Kedzierska, K, Moore, C, Belnoue-Davis, HL, Church, DN
Format: Journal article
Language:English
Published: EMBO Press 2023