Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis

High-risk endometrial cancer has poor prognosis and is increasing in incidence. However, understanding of the molecular mechanisms which drive this disease is limited. We used genetically engineered mouse models (GEMM) to determine the functional consequences of missense and loss of function mutatio...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Brown, M, Leon, A, Kedzierska, K, Moore, C, Belnoue-Davis, HL, Church, DN
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: EMBO Press 2023