Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis

High-risk endometrial cancer has poor prognosis and is increasing in incidence. However, understanding of the molecular mechanisms which drive this disease is limited. We used genetically engineered mouse models (GEMM) to determine the functional consequences of missense and loss of function mutatio...

詳細記述

書誌詳細
主要な著者: Brown, M, Leon, A, Kedzierska, K, Moore, C, Belnoue-Davis, HL, Church, DN
フォーマット: Journal article
言語:English
出版事項: EMBO Press 2023