CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients.
In humans, NK receptors are expressed by natural killer cells and some T cells, the latter of which are preferentially alphabetaTCR+ CD8+ cytolytic T lymphocytes (CTL). In this study we analyzed the expression of nine NK receptors (p58.1, p58.2, p70, p140, ILT2, NKRP1A, ZIN176, CD94 and CD94/NKG2A)...
Autors principals: | Speiser, D, Valmori, D, Rimoldi, D, Pittet, M, Liénard, D, Cerundolo, V, MacDonald, H, Cerottini, J, Romero, P |
---|---|
Format: | Journal article |
Idioma: | English |
Publicat: |
1999
|
Ítems similars
-
In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes.
per: Speiser, D, et al.
Publicat: (1999) -
Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376.
per: Valmori, D, et al.
Publicat: (1999) -
Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes.
per: Romero, P, et al.
Publicat: (1998) -
High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals.
per: Pittet, M, et al.
Publicat: (1999) -
Tetramer-guided analysis of TCR beta-chain usage reveals a large repertoire of melan-A-specific CD8+ T cells in melanoma patients.
per: Valmori, D, et al.
Publicat: (2000)