Synergistic complement lysis by monoclonal antibodies to the human leukocyte common antigen requires both the classical and alternative pathways.

In a previous study we isolated a series of rat monoclonal antibodies to the human leukocyte common (LC) antigen and demonstrated that synergistic complement lysis was possible between IgG2b antibodies which recognised different epitopes. In this report we have examined the mechanisms that were invo...

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Bibliographic Details
Main Authors: Bindon, C, Hale, G, Hughes-Jones, N, Gorick, B, Waldmann, H
Format: Journal article
Language:English
Published: 1987