Synergistic complement lysis by monoclonal antibodies to the human leukocyte common antigen requires both the classical and alternative pathways.
In a previous study we isolated a series of rat monoclonal antibodies to the human leukocyte common (LC) antigen and demonstrated that synergistic complement lysis was possible between IgG2b antibodies which recognised different epitopes. In this report we have examined the mechanisms that were invo...
Main Authors: | Bindon, C, Hale, G, Hughes-Jones, N, Gorick, B, Waldmann, H |
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פורמט: | Journal article |
שפה: | English |
יצא לאור: |
1987
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פריטים דומים
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Therapeutic potential of monoclonal antibodies to the leukocyte-common antigen. Synergy and interference in complement-mediated lysis.
מאת: Bindon, C, et al.
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Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies.
מאת: Bindon, C, et al.
יצא לאור: (1988) -
Therapeutic potential of monoclonal antibodies to the leucocyte common antigen.
מאת: Bindon, C, et al.
יצא לאור: (1985) -
Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen.
מאת: Xia, M, et al.
יצא לאור: (1993) -
Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q.
מאת: Bindon, C, et al.
יצא לאור: (1988)