Factor-inhibiting HIF-1 (FIH-1) is required for human vascular endothelial cell survival

<p style="text-align:justify;"> Factor-inhibiting hypoxia-inducible factor (HIF)-1 (FIH-1) is an asparaginyl β-hydroxylase enzyme that was initially found to hydroxylate the HIF-α, preventing its transcriptional activity and leading to adaptive responses to hypoxia. More recently, o...

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Detalhes bibliográficos
Principais autores: Kiriakidis, S, Henze, A, Kruszynska-Ziaja, I, Skobridis, K, Theodorou, V, Paleolog, E, Mazzone, M
Formato: Journal article
Idioma:English
Publicado em: Federation of American Society of Experimental Biology 2015