Factor-inhibiting HIF-1 (FIH-1) is required for human vascular endothelial cell survival

Factor-inhibiting HIF-1 (FIH-1) is required for human vascular endothelial cell survival

<p style="text-align:justify;"> Factor-inhibiting hypoxia-inducible factor (HIF)-1 (FIH-1) is an asparaginyl β-hydroxylase enzyme that was initially found to hydroxylate the HIF-α, preventing its transcriptional activity and leading to adaptive responses to hypoxia. More recently, o...

Podrobná bibliografie
Hlavní autoři:	Kiriakidis, S, Henze, A, Kruszynska-Ziaja, I, Skobridis, K, Theodorou, V, Paleolog, E, Mazzone, M
Médium:	Journal article
Jazyk:	English
Vydáno:	Federation of American Society of Experimental Biology 2015

Podobné jednotky

Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis.
Autor: Khan, M, a další
Vydáno: (2011)

The role of factor inhibiting HIF (FIH-1) in inhibiting HIF-1 transcriptional activity in glioblastoma multiforme.
Autor: Enfeng Wang, a další
Vydáno: (2014-01-01)

Factor inhibiting HIF (FIH1) modulates cardiac function and metabolism
Autor: Holliday, J, a další
Vydáno: (2018)

Investigating the role of factor inhibiting HIF (FIH) in tumourigenesis
Autor: Ma, J
Vydáno: (2017)

Factor-inhibiting HIF (FIH) promotes lung cancer progression
Autor: Ana García-del Río, a další
Vydáno: (2023-10-01)

Nuclear entry and export of FIH are mediated by HIF1α and exportin1 respectively
Autor: Wang, Y, a další
Vydáno: (2018)

Vascular endothelial growth factor signalling in endothelial cell survival: a role for NFkappaB.
Autor: Grosjean, J, a další
Vydáno: (2006)

Signalling cross talk of the HIF system: involvement of the FIH protein.
Autor: Coleman, M, a další
Vydáno: (2009)

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
Autor: Hewitson, K, a další
Vydáno: (2002)

Overexpression of the HIF hydroxylases PHD1, PHD2, PHD3 and FIH are individually and collectively unfavorable prognosticators for NSCLC survival.
Autor: Sigve Andersen, a další
Vydáno: (2011-01-01)

FIH permits NAA10 to catalyze the oxygen-dependent lysyl-acetylation of HIF-1α
Autor: Jengmin Kang, a další
Vydáno: (2018-10-01)

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).
Autor: Cockman, M, a další
Vydáno: (2006)

The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity.
Autor: Masson, N, a další
Vydáno: (2012)

The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity
Autor: Masson, N, a další
Vydáno: (2012)

Evidence that two enzyme-derived histidine ligands are sufficient for iron binding and catalysis by factor inhibiting HIF (FIH).
Autor: Hewitson, K, a další
Vydáno: (2008)

Fih attenuates the hypoxic tolerance of Megalobrama amblycephala by inhibiting the activity of hypoxia-inducible factor alpha (hif-α)
Autor: Jun Li, a další
Vydáno: (2024-08-01)

ceRNA regulatory network of FIH inhibitor as a radioprotector for gastrointestinal toxicity by activating the HIF-1 pathway
Autor: Yu-wei Yang, a další
Vydáno: (2021-09-01)

HIF-isoforms have divergent roles in the angiogenesis of colorectal cancer
Autor: Thairu, N, a další
Vydáno: (2012)

Vascular endothelium--role in chronic inflammatory disease.
Autor: Kiriakidis, S, a další
Vydáno: (2013)

Hypoxia. The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis.
Autor: Muz, B, a další
Vydáno: (2009)

Studies on FIH interactions
Autor: Leissing, T
Vydáno: (2017)

HIF1 and ID1 Interplay Confers Adaptive Survival to HIF1α-Inhibition
Autor: Hao Geng, a další
Vydáno: (2021-11-01)

Activation of hypoxia-inducible factor (HIF) pathway in varicose veins
Autor: Lim, C, a další
Vydáno: (2011)

The inhibition of factor inhibiting hypoxia-inducible factor (FIH) by beta-oxocarboxylic acids.
Autor: Banerji, B, a další
Vydáno: (2005)

The relationship between factor inhibiting HIF-1-alpha (HIF1AN( expression and vascular invasion in colon cancer
Autor: Reza Najafipour, a další
Vydáno: (2016-10-01)

Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway.
Autor: Giatromanolaki, A, a další
Vydáno: (2008)

Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway
Autor: Giatromanolaki, A, a další
Vydáno: (2008)

Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases.
Autor: Lancaster, D, a další
Vydáno: (2004)

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1.
Autor: Carsten C Scholz, a další
Vydáno: (2016-01-01)

Caenorhabditis elegans HIF-1 Is Broadly Required for Survival in Hydrogen Sulfide
Autor: Irini Topalidou, a další
Vydáno: (2017-11-01)

FIH-1, a novel interactor of mindbomb, functions as an essential anti-angiogenic factor during zebrafish vascular development.
Autor: Ju-Hoon So, a další
Vydáno: (2014-01-01)

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
Autor: Stolze, I, a další
Vydáno: (2004)

Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity.
Autor: Lancaster, D, a další
Vydáno: (2004)

CircCDR1as Suppresses Bone Microvascular Endothelial Cell Activity and Angiogenesis Through Targeting miR‐135b/ FIH‐1 Axis
Autor: Zheng Mao, a další
Vydáno: (2021-04-01)

La verità, vi prego, sul criterio del creditore privato: Commissione c. FIH Holding e FIH Erhvervsbank
Autor: Alessandro Rosanò
Vydáno: (2019-03-01)

Advanced glycation end products (AGEs) augment production of vascular endothelial growth factor (VEGF) and tumor necrosis factor alpha (TNF alpha) in human monocyte-derived macrophages.
Autor: Pertynska-Marczewska, M, a další
Vydáno: (2003)

Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1
Autor: Christina Pickel, a další
Vydáno: (2019-09-01)

STEAP4 Inhibits HIF-1α/PKM2 Signaling and Reduces High Glucose-Induced Apoptosis of Retinal Vascular Endothelial Cells
Autor: Liu L, a další
Vydáno: (2020-07-01)

HIF-1 reduces ischaemia-reperfusion injury in the heart by targeting the mitochondrial permeability transition pore.
Autor: Ong, S, a další
Vydáno: (2014)

Rapamycin inhibits proliferation of hemangioma endothelial cells by reducing HIF-1-dependent expression of VEGF.
Autor: Damian Medici, a další
Vydáno: (2012-01-01)