Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension.

Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension.

BACKGROUND: Pulmonary hypertension is a fatal disease characterized by vasoconstriction and vascular remodeling. Loss of endothelial nitric oxide bioavailability is implicated in pulmonary hypertension pathogenesis. Recent evidence suggests that the cofactor tetrahydrobiopterin (BH4) is an importan...

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Manylion Llyfryddiaeth
Prif Awduron:	Khoo, J, Zhao, L, Alp, N, Bendall, J, Nicoli, T, Rockett, K, Wilkins, MR, Channon, K
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2005

Eitemau Tebyg

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Tetrahydrobiopterin (BH4) Improves Endothelial Cell Survival After Vascular Injury
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