Detecting RNA-protein proximity at DNA double-strand breaks using combined fluorescence in situ hybridization with proximity ligation assay
<p>RNA transcribed at DNA double-strand breaks (DSBs) contributes to accurate DNA repair. Here, using the repair factors 53BP1 and TIRR as examples, we combine the fluorescence <i>in situ</i> hybridization (FISH) and proximity ligation assay (PLA) techniques to determine protein pr...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Cell Press
2023
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