The HIF pathway: implications for patterns of gene expression in cancer.

Regulation of the growth and metabolism of large organisms is tightly constrained by the need for precise oxygen homeostasis. Work on control of the haematopoietic growth factor erythropoietin has led to the recognition of a widespread transcriptional response to hypoxia which provides insights into...

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Bibliographic Details
Main Authors: Wykoff, C, Pugh, C, Harris, A, Maxwell, P, Ratcliffe, P
Format: Journal article
Language:English
Published: 2001