The HIF pathway: implications for patterns of gene expression in cancer.
Regulation of the growth and metabolism of large organisms is tightly constrained by the need for precise oxygen homeostasis. Work on control of the haematopoietic growth factor erythropoietin has led to the recognition of a widespread transcriptional response to hypoxia which provides insights into...
Hlavní autoři: | Wykoff, C, Pugh, C, Harris, A, Maxwell, P, Ratcliffe, P |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2001
|
Podobné jednotky
-
Activation of the HIF pathway in cancer.
Autor: Maxwell, P, a další
Vydáno: (2001) -
Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling.
Autor: Wykoff, C, a další
Vydáno: (2000) -
The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages.
Autor: Talks, K, a další
Vydáno: (2000) -
Targeting tumors through the HIF system.
Autor: Ratcliffe, P, a další
Vydáno: (2000) -
Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing.
Autor: Mole, D, a další
Vydáno: (2001)