Blocking development of a CD8+ T cell response by targeting lymphatic recruitment of APC.
Generating a protective immune response to viral infection is known to depend upon the priming and clonal expansion of virus-specific CD8(+) T cells by Ag-loaded dendritic cells (DC) within secondary lymphoid tissue. However, the actual initiation of the response involves critical upstream events th...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2009
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