Identification of antigen-specific B-cell receptor sequences from the total B-cell repertoire

Advances in next-generation sequencing now allow characterization of the global B-cell receptor (BCR) heavy-chain repertoire at a level that reflects its huge diversity. This technology has provided great insight into the structure of the BCR repertoire and how it responds to specific antigen stimu...

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Autori principali: Galson, J, Kelly, D, Trück, J
Natura: Journal article
Pubblicazione: Begell House 2016