Identification of antigen-specific B-cell receptor sequences from the total B-cell repertoire

Advances in next-generation sequencing now allow characterization of the global B-cell receptor (BCR) heavy-chain repertoire at a level that reflects its huge diversity. This technology has provided great insight into the structure of the BCR repertoire and how it responds to specific antigen stimu...

Description complète

Détails bibliographiques
Auteurs principaux: Galson, J, Kelly, D, Trück, J
Format: Journal article
Publié: Begell House 2016