A non-canonical voltage-sensing mechanism controls gating in K2P K(+) channels

Two-pore domain (K2P) K(+) channels are major regulators of excitability that endow cells with an outwardly rectifying background "leak" conductance. In some K2P channels, strong voltage-dependent activation has been observed, but the mechanism remains unresolved because they lack a canoni...

Ful tanımlama

Detaylı Bibliyografya
Asıl Yazarlar: Schewe, M, Nematian-Ardestani, E, Sun, H, Musinszki, M, Cordeiro, S, Bucci, G, de Groot, B, Tucker, S, Rapedius, M, Baukrowitz, T
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: Cell Press 2016