A non-canonical voltage-sensing mechanism controls gating in K2P K(+) channels
Two-pore domain (K2P) K(+) channels are major regulators of excitability that endow cells with an outwardly rectifying background "leak" conductance. In some K2P channels, strong voltage-dependent activation has been observed, but the mechanism remains unresolved because they lack a canoni...
Asıl Yazarlar: | , , , , , , , , , |
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Materyal Türü: | Journal article |
Dil: | English |
Baskı/Yayın Bilgisi: |
Cell Press
2016
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