An ion-channel modulator from the saliva of the brown ear tick has a highly modified Kunitz/BPTI structure.

Ra-KLP, a 75 amino acid protein secreted by the salivary gland of the brown ear tick Rhipicephalus appendiculatus has a sequence resembling those of Kunitz/BPTI proteins. We report the detection, purification and characterization of the function of Ra-KLP. In addition, determination of the three-dim...

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Bibliographic Details
Main Authors: Paesen, G, Siebold, C, Dallas, M, Peers, C, Harlos, K, Nuttall, P, Nunn, M, Stuart, D, Esnouf, R
Format: Journal article
Language:English
Published: 2009