Understanding the role of islet development in type 2 diabetes susceptibility

<p>Most variants associated with type 2 diabetes (T2D) predisposition in genome-wide association studies (GWAS) act through defects in insulin secretion. In principle, these could result from deficiencies in islet development and/or mature islet function: most functional studies have focused o...

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Bibliographic Details
Main Author: Pérez Alcántara, MC
Other Authors: McCarthy, M
Format: Thesis
Language:English
Published: 2019
Subjects: