HIV-1 adaptation to antigen processing results in population-level immune evasion and affects subtype diversification.

The recent HIV-1 vaccine failures highlight the need to better understand virus-host interactions. One key question is why CD8(+) T cell responses to two HIV-Gag regions are uniquely associated with delayed disease progression only in patients expressing a few rare HLA class I variants when these re...

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Detalhes bibliográficos
Principais autores:	Tenzer, S, Crawford, H, Pymm, P, Gifford, R, Sreenu, V, Weimershaus, M, de Oliveira, T, Burgevin, A, Gerstoft, J, Akkad, N, Lunn, D, Fugger, L, Bell, J, Schild, H, van Endert, P, Iversen, A
Formato:	Journal article
Idioma:	English
Publicado em:	2014

HIV-1 adaptation to antigen processing results in population-level immune evasion and affects subtype diversification.

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