Diagnosis of Streptococcus pneumoniae infections in adults with bacteremia and community-acquired pneumonia: clinical comparison of pneumococcal PCR and urinary antigen detection.

The diagnosis of severe Streptococcus pneumoniae infection relies heavily on insensitive culture techniques. To improve the usefulness of PCR assays, we developed a dual-PCR protocol (targeted at pneumolysin and autolysin) for EDTA blood samples. This was compared to the Binax NOW S. pneumoniae urin...

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Bibliographic Details
Main Authors: Smith, MD, Sheppard, C, Hogan, A, Harrison, T, Dance, D, Derrington, P, George, R
Format: Journal article
Language:English
Published: 2009