Differential interactions of nateglinide and repaglinide on the human beta-cell sulphonylurea receptor 1.

Repaglinide and nateglinide represent a new class of insulin secretagogues, structurally unrelated to sulphonylureas, that were developed for the treatment of type 2 diabetes. The inhibitory effect of these drugs was investigated on recombinant wild-type and mutant Kir6.2/SUR1 channels expressed in...

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Bibliografiset tiedot
Päätekijät: Hansen, A, Christensen, I, Hansen, J, Carr, R, Ashcroft, F, Wahl, P
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2002