Differential interactions of nateglinide and repaglinide on the human beta-cell sulphonylurea receptor 1.
Repaglinide and nateglinide represent a new class of insulin secretagogues, structurally unrelated to sulphonylureas, that were developed for the treatment of type 2 diabetes. The inhibitory effect of these drugs was investigated on recombinant wild-type and mutant Kir6.2/SUR1 channels expressed in...
Κύριοι συγγραφείς: | , , , , , |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2002
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