Safety and immunogenicity of ChAdOx1 85A prime followed by MVA85A boost compared with BCG revaccination among Ugandan adolescents who received BCG at birth: a randomised, open-label trial

Safety and immunogenicity of ChAdOx1 85A prime followed by MVA85A boost compared with BCG revaccination among Ugandan adolescents who received BCG at birth: a randomised, open-label trial

<p><strong>Background</strong> BCG confers reduced, variable protection against pulmonary tuberculosis. A more effective vaccine is needed. We evaluated the safety and immunogenicity of candidate regimen ChAdOx1 85A–MVA85A compared with BCG revaccination among Ugandan adolescents.&...

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Bibliographic Details
Main Authors: Wajja, A, Nassanga, B, Natukunda, A, Serubanja, J, Tumusiime, J, Akurut, H, Oduru, G, Nassuuna, J, Kabagenyi, J, Morrison, H, Scott, H, Doherty, RP, Marshall, JL, Puig, IC, Cose, S, Kaleebu, P, Webb, EL, Satti, I, McShane, H, Elliott, AM, TB042 Study Team
Format: Journal article
Language:English
Published: Elsevier 2023

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