Functional characterisation of synuclein-based novel genetic mouse models

Functional characterisation of synuclein-based novel genetic mouse models

<p>Synucleins are highly conserved presynaptic proteins with unknown function. α-synuclein plays a key role regulating dopamine homeostasis and is intimately involved in Parkinson’s disease (PD) pathogenesis. However, the normal/pathological role of α-synuclein remains unidentified. Studies ex...

Mô tả đầy đủ

Chi tiết về thư mục
Tác giả chính:	Anwar, S
Tác giả khác:	Wade-Martins, R
Định dạng:	Luận văn
Ngôn ngữ:	English
Được phát hành:	2011
Những chủ đề:	Neuroscience Medical Sciences Neurogenetics

Những quyển sách tương tự

The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration
Bằng: Paracchini, S, et al.
Được phát hành: (2006)

Influence of age, sex and genetic factors on the human brain
Bằng: McKay, DR, et al.
Được phát hành: (2014)

A novel mouse model of creatine transporter deficiency [v1; ref status: indexed, http://f1000r.es/4f8]
Bằng: Laura Baroncelli, et al.
Được phát hành: (2014-09-01)

Rate of tau propagation is a heritable disease trait in genetically diverse mouse strains
Bằng: Lindsay A. Welikovitch, et al.
Được phát hành: (2023-02-01)

Molecular Genetics of Language Impairment
Bằng: Nudel, R
Được phát hành: (2015)

A KO mouse model for the lncRNA Lhx1os produces motor neuron alterations and locomotor impairment
Bằng: Flaminia Pellegrini, et al.
Được phát hành: (2023-01-01)

Genetic basis of neurocognitive decline and reduced white-matter integrity in normal human brain aging
Bằng: Glahn, D, et al.
Được phát hành: (2013)

The role of polycomb repressive complex 2 in postnatal subventricular zone neural stem/progenitor cell self-renewal and multipotency
Bằng: Chang, EH
Được phát hành: (2012)

Identification of the transneuronal homeostatic machinery at a central synapse
Bằng: Harrell, E, et al.
Được phát hành: (2014)

GPER1 Signaling Initiates Migration of Female V-SVZ-Derived Cells
Bằng: Iris Haumann, et al.
Được phát hành: (2020-05-01)

Genetic architecture of declarative memory: implications for complex illnesses
Bằng: Bearden, C, et al.
Được phát hành: (2012)

Genetic influence on the working memory circuitry: Behavior, structure, function and extensions to illness
Bằng: Karlsgodt, K, et al.
Được phát hành: (2011)

Computational neurogenetic modeling /
Bằng: Benuskova, Lubica, 1958-, et al.
Được phát hành: (2007)

Mate copying requires the coincidence detector Rutabaga in the mushroom bodies of Drosophila melanogaster
Bằng: Sabine Nöbel, et al.
Được phát hành: (2023-09-01)

Characterisation of pitch: an early onset model of sensorineural deafness
Bằng: Carrott, L
Được phát hành: (2014)

Social Isolation and Enrichment Induce Unique miRNA Signatures in the Prefrontal Cortex and Behavioral Changes in Mice
Bằng: Natalia Popa, et al.
Được phát hành: (2020-12-01)

Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
Bằng: Safak Caglayan, et al.
Được phát hành: (2020-06-01)

Computational neuroscience : simulated demyelinating neuropathies and neuronopathies /
Bằng: Stephanova, Diana Ivanova 545416, et al.
Được phát hành: (2013)

Hyperactive mTORC1 disrupts habenula function and light preference in zebrafish model of Tuberous sclerosis complex
Bằng: Olga Doszyn, et al.
Được phát hành: (2024-06-01)

Neural tube patterning: From a minimal model for rostrocaudal patterning toward an integrated 3D model
Bằng: Max Brambach, et al.
Được phát hành: (2021-06-01)

The Redox Activity of Protein Disulfide Isomerase Inhibits ALS Phenotypes in Cellular and Zebrafish Models
Bằng: Sonam Parakh, et al.
Được phát hành: (2020-05-01)

The genetics of handedness and dyslexia
Bằng: Brandler, W
Được phát hành: (2014)

Identification of epigenetic regulators of RNA editing mechanisms
Bằng: Buss, G
Được phát hành: (2023)

The converging roles of Batten disease proteins in neurodegeneration and cancer
Bằng: Shyong Quan Yap, et al.
Được phát hành: (2021-04-01)

Dissecting the functions of DISC1
Bằng: Carless, M, et al.
Được phát hành: (2011)

The behavioural and molecular characterisation of a novel LRRK2 BAC transgenic rat model of Parkinson’s disease
Bằng: Sloan, M, et al.
Được phát hành: (2014)

Functional investigation of microRNA pathways in human speech and language disorders
Bằng: Ho, J
Được phát hành: (2014)

Molecular and neural mechanisms of olfactory decision making in Drosophila melanogaster
Bằng: Ferreira, C
Được phát hành: (2015)

Methods in genomic neuroscience /
Bằng: Chin, Hemin R., et al.
Được phát hành: (2001)

Reduced white matter integrity in sibling pairs discordant for bipolar disorder
Bằng: Sprooten, E, et al.
Được phát hành: (2013)

Blood pressure and cerebral white matter share common genetic factors in Mexican Americans
Bằng: Kochunov, P, et al.
Được phát hành: (2011)

Investigating the roles of zinc finger homeobox 3 in circadian rhythms
Bằng: Edwards, JK
Được phát hành: (2013)

Model systems for exploring new therapeutic interventions and disease mechanisms in spinal muscular atrophies (SMAs)
Bằng: Sleigh, JN
Được phát hành: (2012)

Murine Cep290 phenotypes are modified by genetic backgrounds and provide an impetus for investigating disease modifier alleles [version 1; referees: 2 approved]
Bằng: Simon Ramsbottom, et al.
Được phát hành: (2015-08-01)

Fetal sex-specific epigenetic associations with prenatal maternal depressive symptoms
Bằng: Michelle Z.L. Kee, et al.
Được phát hành: (2022-09-01)

Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes
Bằng: Carless, M, et al.
Được phát hành: (2011)

Human brain harbors single nucleotide somatic variations in functionally relevant genes possibly mediated by oxidative stress [version 3; referees: 2 approved]
Bằng: Anchal Sharma, et al.
Được phát hành: (2017-01-01)

Using fast-scan cyclic voltammetry to investigate monoamine release in BAC transgenic rodent models of Parkinson's Disease
Bằng: Potgieter, D
Được phát hành: (2014)

Subplate populations in normal and pathological cortical development
Bằng: Oeschger, F
Được phát hành: (2011)

Molecular and behavioural characterisation of novel alpha-synuclein BAC transgenic mouse models of Parkinson's disease
Bằng: Janezic, S
Được phát hành: (2013)