Crystallization and preliminary X-ray analysis of Leishmania major glyoxalase I

Glyoxalase I (GLO1) is a putative drug target for trypanosomatids, which are pathogenic protozoa that include the causative agents of leishmaniasis. Significant sequence and functional differences between Leishmania major and human GLO1 suggest that it may make a suitable template for rational inhib...

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Detalhes bibliográficos
Main Authors: Ariza, A, Vickers, T, Greig, N, Fairlamb, A, Bond, C
Formato: Journal article
Idioma:English
Publicado em: International Union of Crystallography 2005