Native-like SARS-CoV-2 spike glycoprotein expressed by ChAdOx1 nCoV-19/AZD1222 vaccine

Vaccine development against the SARS-CoV-2 virus focuses on the principal target of the neutralizing immune response, the spike (S) glycoprotein. Adenovirus-vectored vaccines offer an effective platform for the delivery of viral antigen, but it is important for the generation of neutralizing antibod...

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Bibliographic Details
Main Authors: Watanabe, Y, Mendonça, L, Allen, ER, Howe, A, Lee, M, Allen, JD, Chawla, H, Pulido, D, Donnellan, F, Davies, H, Ulaszewska, M, Belij-Rammerstorfer, S, Morris, S, Krebs, A-S, Dejnirattisai, W, Mongkolsapaya, J, Supasa, P, Screaton, GR, Green, CM, Lambe, T, Zhang, P, Gilbert, SC, Crispin, M
Format: Journal article
Language:English
Published: American Chemical Society 2021