Human T-cell leukemia virus type 1 Tax protein binds to assembled nuclear proteasomes and enhances their proteolytic activity.

The human T-cell leukemia virus type 1 (HTLV-1) Tax protein activates the HTLV-1 long terminal repeat and key regulatory proteins involved in inflammation, activation, and proliferation and may induce cell transformation. Tax is also the immunodominant target antigen for cytotoxic T cells in HTLV-1...

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Bibliographic Details
Main Authors: Hemelaar, J, Bex, F, Booth, B, Cerundolo, V, McMichael, A, Daenke, S
Format: Journal article
Language:English
Published: 2001